The Pseudomonas aeruginosa Quorum-Sensing Molecule N-3-(Oxododecanoyl)-l-Homoserine Lactone Inhibits T-Cell Differentiation and Cytokine Production by a Mechanism Involving an Early Step in T-Cell Activation

The Pseudomonas aeruginosa quorum-sensing molecule N-3-(oxododecanoyl)-l-homoserine lactone (OdDHL) has been reported to have immunomodulatory activity in several systems, although the mechanism of that activity remains to be fully characterized. We demonstrate here, using a defined in vitro model o...

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Main Authors: Ritchie, A. J., Jansson, A., Stallberg, J., Nilsson, P., Lysaght, P., Cooley, M. A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Host Response and Inflammation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064928/
https://ncbi.nlm.nih.gov/pubmed/15731065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1648-1655.2005
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