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Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction

Hyaluronan is a major molecule in joint fluid and plays a crucial role in joint motion and the maintenance of joint homeostasis. The concentration and average molecular weight of hyaluronan in the joint fluids are reduced in osteoarthritis and rheumatoid arthritis. To elucidate the underlying mechan...

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Autors principals: Yoshida, Mamoru, Sai, Shigaku, Marumo, Keishi, Tanaka, Takaaki, Itano, Naoki, Kimata, Koji, Fujii, Katsuyuki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064865/
https://ncbi.nlm.nih.gov/pubmed/15535829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1223
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