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Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situ hybridization and immunohistochemistry

INTRODUCTION: One of the most common genetic aberrations associated with breast cancer is the amplification and overexpression of the ERBB2 proto-oncogene located at chromosome 17, bands q12-21. The amplification/overexpression occurs in 25 to 30% of all breast cancers. In breast cancer, aneusomy of...

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Detalhes bibliográficos
Main Authors: Salido, Marta, Tusquets, Ignasi, Corominas, Josep M, Suarez, Marta, Espinet, Blanca, Corzo, Cristina, Bellet, Meritxell, Fabregat, Xavier, Serrano, Sergi, Solé, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064140/
https://ncbi.nlm.nih.gov/pubmed/15743507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr996
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