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Do early premalignant changes in normal breast epithelial cells predict cancer development?
A recent report suggests that, in an in vitro model of premalignant breast cells (vHMECs), silencing of INK4A gene is accompanied by over-expression of cyclo-oxygenase (COX)-2. This suggests that COX-2 over-expression may be an early event in breast cancer aetiology permitting clones within the norm...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1064113/ https://ncbi.nlm.nih.gov/pubmed/15642177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr967 |
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