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Endocrinology and hormone therapy in breast cancer: Aromatase inhibitors versus antioestrogens

Endocrine therapies act by either blocking or downregulating the oestrogen receptor or by reducing oestrogen concentrations around and within the cancer cell. In postmenopausal women, oestrogen suppression is achieved by inhibition of the enzyme aromatase by aromatase inhibitors (AIs). Modern AIs (a...

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Bibliografiske detaljer
Main Authors: Howell, Anthony, Dowsett, Mitch
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064088/
https://ncbi.nlm.nih.gov/pubmed/15535858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr945
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