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Frequency of CHEK2 mutations in a population based, case–control study of breast cancer in young women

INTRODUCTION: The cell-cycle checkpoint kinase (CHEK)2 protein truncating mutation 1100delC has been associated with increased risk for breast or prostate cancer. Multiple studies have found an elevated frequency of the 1100delC variant in specific stratifications of breast cancer patients with a fa...

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Main Authors: Friedrichsen, Danielle M, Malone, Kathleen E, Doody, David R, Daling, Janet R, Ostrander, Elaine A
格式: Artigo
語言:Inglês
出版: BioMed Central 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064080/
https://ncbi.nlm.nih.gov/pubmed/15535844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr933
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