Cytoplasmic Control of Premature Activation of a Secreted Protease Zymogen: Deletion of Staphostatin B (SspC) in Staphylococcus aureus 8325-4 Yields a Profound Pleiotropic Phenotype

The cytoplasmic protein SspC of Staphylococcus aureus, referred to as staphostatin B, is a very specific, tightly binding inhibitor of the secreted protease staphopain B (SspB). SspC is hypothesized to protect intracellular proteins against proteolytic damage by prematurely folded and activated stap...

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Bibliografiska uppgifter
Huvudupphovsmän: Shaw, Lindsey N., Golonka, Ewa, Szmyd, Grzegorz, Foster, Simon J., Travis, James, Potempa, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Molecular Biology of Pathogens
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064019/
https://ncbi.nlm.nih.gov/pubmed/15716447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.5.1751-1762.2005
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