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A critical role for the Sp1-binding sites in the transforming growth factor-β-mediated inhibition of lipoprotein lipase gene expression in macrophages

Increasing evidence suggests that the cytokine transforming growth factor-β (TGF-β) inhibits the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by macrophages has been implicated in the pathogenesis of atherosclerosis by stimulating the uptake of lipoprotein particles....

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Detalles Bibliográficos
Main Authors: Irvine, Scott A., Foka, Pelagia, Rogers, Sarah A., Mead, James R., Ramji, Dipak P.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1062872/
https://ncbi.nlm.nih.gov/pubmed/15755745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki280
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