Deficits in Motor Coordination with Aberrant Cerebellar Development in Mice Lacking Testicular Orphan Nuclear Receptor 4

Since testicular orphan nuclear receptor 4 (TR4) was cloned, its physiological function has remained largely unknown. Throughout postnatal development, TR4-knockout (TR4(−/−)) mice exhibited behavioral deficits in motor coordination, suggesting impaired cerebellar function. Histological examination...

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Autores principales: Chen, Yei-Tsung, Collins, Loretta L., Uno, Hideo, Chang, Chawnshang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061629/
https://ncbi.nlm.nih.gov/pubmed/15767677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.7.2722-2732.2005
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