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Inactivation of the Pre-mRNA Cleavage and Polyadenylation Factor Pfs2 in Fission Yeast Causes Lethal Cell Cycle Defects

Faithful chromosome segregation is fundamentally important for the maintenance of genome integrity and ploidy. By isolating conditional mutants defective in chromosome segregation in the fission yeast Schizosaccharomyces pombe, we identified a role for the essential gene pfs2 in chromosome dynamics....

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Detalhes bibliográficos
Main Authors: Wang, Shao-Win, Asakawa, Kazuhide, Win, Thein Z., Toda, Takashi, Norbury, Chris J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061621/
https://ncbi.nlm.nih.gov/pubmed/15743824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2288-2296.2005
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