Inactivation of the Pre-mRNA Cleavage and Polyadenylation Factor Pfs2 in Fission Yeast Causes Lethal Cell Cycle Defects

Faithful chromosome segregation is fundamentally important for the maintenance of genome integrity and ploidy. By isolating conditional mutants defective in chromosome segregation in the fission yeast Schizosaccharomyces pombe, we identified a role for the essential gene pfs2 in chromosome dynamics....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Shao-Win, Asakawa, Kazuhide, Win, Thein Z., Toda, Takashi, Norbury, Chris J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061621/
https://ncbi.nlm.nih.gov/pubmed/15743824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2288-2296.2005
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