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Novel Checkpoint Response to Genotoxic Stress Mediated by Nucleolin-Replication Protein A Complex Formation

Human replication protein A (RPA), the primary single-stranded DNA-binding protein, was previously found to be inhibited after heat shock by complex formation with nucleolin. Here we show that nucleolin-RPA complex formation is stimulated after genotoxic stresses such as treatment with camptothecin...

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Bibliografische gegevens
Hoofdauteurs: Kim, Kyung, Dimitrova, Diana D., Carta, Kristine M., Saxena, Anjana, Daras, Mariza, Borowiec, James A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061594/
https://ncbi.nlm.nih.gov/pubmed/15743838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2463-2474.2005
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