Human Immunodeficiency Virus Type 1 Nef Potently Induces Apoptosis in Primary Human Brain Microvascular Endothelial Cells via the Activation of Caspases

The lentiviral protein Nef plays a major role in the pathogenesis of human immunodeficiency virus type I (HIV-1) infection. Although the exact mechanisms of its actions are not fully understood, Nef has been shown to be essential for the maintenance of high-titer viral replication and disease pathog...

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Detalhes bibliográficos
Main Authors: Acheampong, Edward A., Parveen, Zahida, Muthoga, Lois W., Kalayeh, Mehrnush, Mukhtar, Muhammad, Pomerantz, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061575/
https://ncbi.nlm.nih.gov/pubmed/15767427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4257-4269.2005
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