In Vitro Activities of Several Diaminomethylpyridopyrimidines against Mycobacterium avium Complex

Three recently synthesized dihydrofolate reductase (DHFR) inhibitors designated SoRI 8890, 8895, and 8897 were evaluated for their in vitro activities against 25 isolates of Mycobacterium avium complex. The MICs at which 50 and 90% of isolates were inhibited were 1 and 2, 4 and 8, and 4 and 8 μg/ml...

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Main Authors: Shoen, Carolyn M., Choromanska, Olga, Reynolds, Robert C., Piper, James R., Johnson, Cheryl A., Cynamon, Michael H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC106045/
https://ncbi.nlm.nih.gov/pubmed/9835537
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