Joint Tolerance to β-Lactam and Fluoroquinolone Antibiotics in Escherichia coli Results from Overexpression of hipA

The basis of joint tolerance to β-lactam and fluoroquinolone antibiotics in Escherichia coli mediated by hipA was examined. An antibiotic tolerance phenotype was produced by overexpression of hipA under conditions that did not affect the growth rate of the organism. Overexpressing hipA probably decr...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Falla, Timothy J., Chopra, Ian
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106036/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3282
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