Rapid Emergence of High-Level Resistance to Quinolones in Campylobacter jejuni Associated with Mutational Changes in gyrA and parC

Quinolone resistance in clinical isolates of Campylobacter jejuni in Sweden increased more than 20-fold at the beginning of the 1990s. Resistance to 125 μg of ciprofloxacin per ml in clinical isolates was associated with chromosomal mutations in C. jejuni leading to a Thr-86-Ile substitution in the...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Gibreel, Amera, Sjögren, Eva, Kaijser, Bertil, Wretlind, Bengt, Sköld, Ola
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3276
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