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In Vitro and In Vivo Antibacterial Activities of OPC-20011, a Novel Parenteral Broad-Spectrum 2-Oxaisocephem Antibiotic

OPC-20011, a new parenteral 2-oxaisocephem antibiotic, has an oxygen atom at the 2- position of the cephalosporin frame. OPC-20011 had the best antibacterial activities against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, and penicillin...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Matsumoto, Makoto, Tamaoka, Hisashi, Ishikawa, Hiroshi, Kikuchi, Mikio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2943
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