Pharmacodynamics of (−)-β-2′,3′-Dideoxy-3′-Thiacytidine in Chronically Virus-Infected Woodchucks Compared to Its Pharmacodynamics in Humans

The pharmacodynamics of (−)-β-2′,3′-dideoxy-3′-thiacytidine (3TC) was studied in chronically woodchuck hepatitis virus-infected woodchucks and compared to that in previous studies in hepatitis B virus (HBV)-infected humans. Net depletion rates of serum virus DNA in woodchucks receiving 3TC were mode...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Hurwitz, Selwyn J., Tennant, Bud C., Korba, Brent E., Gerin, John L., Schinazi, Raymond F.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1998
Matèries:	Antiviral Agents
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2804
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