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Enhancement of Antimicrobial Activity of Neuropeptide Y by N-Terminal Truncation

The activity of neuropeptide Y (NPY) against Candida albicans, which was revealed to be fungicidal, was enhanced significantly by the truncation of amino acid residues at the N terminus. The most active peptides (MICs, approximately 1 μM) were about 10-fold more potent than the intact NPY (MIC, appr...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Shimizu, Mayumi, Shigeri, Yasushi, Tatsu, Yoshiro, Yoshikawa, Susumu, Yumoto, Noboru
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105930/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2745
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