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Inhibitory Activities of Gatifloxacin (AM-1155), a Newly Developed Fluoroquinolone, against Bacterial and Mammalian Type II Topoisomerases

We determined the inhibitory activities of gatifloxacin against Staphylococcus aureus topoisomerase IV, Escherichia coli DNA gyrase, and HeLa cell topoisomerase II and compared them with those of several quinolones. The inhibitory activities of quinolones against these type II topoisomerases signifi...

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Detalhes bibliográficos
Main Authors: Takei, Masaya, Fukuda, Hideyuki, Yasue, Tokutaro, Hosaka, Masaki, Oomori, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105918/
https://ncbi.nlm.nih.gov/pubmed/9756776
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