Identification of Novel Mutation Patterns in the parC Gene of Ciprofloxacin-Resistant Isolates of Neisseria gonorrhoeae

Of 65 ciprofloxacin-resistant, clinical isolates of Neisseria gonorrhoeae, 5 isolates exhibited ParC mutations previously undescribed in the gonococcus. For isolates containing two ParC mutations (the Ser-87→Ile and Glu-91→Gly mutations and the Gly-85→Cys and Arg116→Leu mutations) the MICs of ciprof...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Trees, David L., Sandul, Amy L., Whittington, William L., Knapp, Joan S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9687414/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.8.2103
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