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Pharmacokinetics of Meropenem in Critically Ill Patients with Acute Renal Failure Treated by Continuous Hemodiafiltration

The pharmacokinetics of meropenem were studied in nine anuric critically ill patients treated by continuous venovenous hemodiafiltration. Peak levels after infusion of 1,000 mg over 30 min amounted to 103.2 ± 45.9 μg/ml, and trough levels at 12 h were 9.6 ± 3.8 μg/ml. A dosage of 1,000 mg of meropen...

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Main Authors: Krueger, W. A., Schroeder, T. H., Hutchison, M., Hoffmann, E., Dieterich, H.-J., Heininger, A., Erley, C., Wehrle, A., Unertl, K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC105844/
https://ncbi.nlm.nih.gov/pubmed/9736574
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