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Sequence of the Gene Encoding a Plasmid-Mediated Cefotaxime-Hydrolyzing Class A β-Lactamase (CTX-M-4): Involvement of Serine 237 in Cephalosporin Hydrolysis

The sequence of the gene encoding a novel cefotaxime-hydrolyzing β-lactamase (CTX-M-4) was determined. It was located in a plasmid harbored by a Salmonella typhimurium strain. CTX-M-4 was similar to the plasmidic cefotaxime-hydrolyzing β-lactamases CTX-M-2 and Toho-1 and related to the chromosomal β...

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Bibliografske podrobnosti
Main Authors: Gazouli, Maria, Tzelepi, Eva, Sidorenko, Sergei V., Tzouvelekis, Leonidas S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC105797/
https://ncbi.nlm.nih.gov/pubmed/9593162
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