Photoaffinity Analog of the Semisynthetic Echinocandin LY303366: Identification of Echinocandin Targets in Candida albicans

The echinocandins are a family of cyclic lipopeptides with potent antifungal activity. These compounds inhibit the synthesis of β-1,3-glucan in fungi. The new semisynthetic echinocandin LY303366 was derivatized to produce a photoactivatable cross-linking echinocandin analog with antifungal activity....

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Bibliographic Details
Main Authors: Radding, Jeffrey A., Heidler, Steven A., Turner, William W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC105773/
https://ncbi.nlm.nih.gov/pubmed/9593148
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