Photoaffinity Analog of the Semisynthetic Echinocandin LY303366: Identification of Echinocandin Targets in Candida albicans

The echinocandins are a family of cyclic lipopeptides with potent antifungal activity. These compounds inhibit the synthesis of β-1,3-glucan in fungi. The new semisynthetic echinocandin LY303366 was derivatized to produce a photoactivatable cross-linking echinocandin analog with antifungal activity....

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Radding, Jeffrey A., Heidler, Steven A., Turner, William W.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Mechanisms of Action: Physiological Effects
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1187
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