Steady-State Pharmacokinetics and Electrocardiographic Pharmacodynamics of Clarithromycin and Loratadine after Individual or Concomitant Administration

To evaluate the potential for an interaction between clarithromycin and loratadine, healthy male volunteers (n = 24) received each of the following regimens according to a randomized crossover design: 500 mg of clarithromycin orally every 12 h (q12h) for 10 days, 10 mg of loratadine orally q24h for...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Carr, Robert A., Edmonds, Anthony, Shi, Harry, Locke, Charles S., Gustavson, Linda E., Craft, J. Carl, Harris, Stuart I., Palmer, Robert
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593146/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1176
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