Fungal β-Tubulin, Expressed as a Fusion Protein, Binds Benzimidazole and Phenylcarbamate Fungicides

Benzimidazoles are important antitubulin agents used in veterinary medicine and plant disease control. Resistance is a practical problem correlated with single amino acid changes in β-tubulin and is often linked to greater sensitivity to phenylcarbamates. This negative cross-resistance creates oppor...

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Bibliographic Details
Main Authors: Hollomon, Derek W., Butters, Jenny A., Barker, Helen, Hall, Len
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC105765/
https://ncbi.nlm.nih.gov/pubmed/9736529
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