Paclitaxel Arrests Growth of Intracellular Toxoplasma gondii

Addition of paclitaxel (Taxol) at a concentration of 1 μM to Toxoplasma gondii-infected human foreskin fibroblasts arrested parasite multiplication. Division of the T. gondii tachyzoite nucleus was inhibited, leading to syncytium-like parasite structures within the fibroblasts by 24 h after infectio...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Estes, Randee, Vogel, Nicolas, Mack, Douglas, McLeod, Rima
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Mechanisms of Action: Physiological Effects
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105729/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9687403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.8.2036
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