Prevalence of a Putative Efflux Mechanism among Fluoroquinolone-Resistant Clinical Isolates of Streptococcus pneumoniae

Twenty-three norfloxacin-selected first-step mutants of Streptococcus pneumoniae showed low-level fluoroquinolone resistance. Their susceptibility to norfloxacin in the presence or absence of reserpine and known efflux pump substrates was determined by an agar dilution method. Five mutants showed fo...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Brenwald, Nigel P., Gill, Martin J., Wise, Richard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9687402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.8.2032
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