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Antibacterial Activity of Gatifloxacin (AM-1155, CG5501, BMS-206584), a Newly Developed Fluoroquinolone, against Sequentially Acquired Quinolone-Resistant Mutants and the norA Transformant of Staphylococcus aureus

Alternate mutations in the grlA and gyrA genes were observed through the first- to fourth-step mutants which were obtained from four Staphylococcus aureus strains by sequential selection with several fluoroquinolones. The increases in the MICs of gatifloxacin accompanying those mutational steps sugg...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Fukuda, Hideyuki, Hori, Satoshi, Hiramatsu, Keiichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9687384/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.8.1917
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