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Effects of DU-6859a, a New Quinolone Antimicrobial, on Theophylline Metabolism in In Vitro and In Vivo Studies

In vitro and in vivo studies were conducted to investigate the drug interaction between a new quinolone antimicrobial, DU-6859a, and theophylline (TP). The effect of DU-6859a on TP metabolism was evaluated in vitro by measuring the rate of TP metabolite formation by using human liver microsomes. DU-...

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Bibliografische gegevens
Hoofdauteurs: Niki, Yoshihito, Itokawa, Kenichi, Okazaki, Osamu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105678/
https://ncbi.nlm.nih.gov/pubmed/9661016
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