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pH Effects on the Activity and Regulation of the NAD Malic Enzyme

The NAD malic enzyme shows a pH optimum of 6.7 when complexed to Mg(2+) and NAD(+) but shifts to 7.0 when the catalytically competent enzyme-substrate (E-S) complex forms upon binding malate(−2). This is characteristic of an induced conformational change. The slope of the V(max) or V(max)/K(m) profi...

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Sonraí Bibleagrafaíochta
Main Authors: Willeford, Kenneth O., Wedding, Randolph T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1987
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1056732/
https://ncbi.nlm.nih.gov/pubmed/16665566
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