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Efficacies of Zinc-Finger-Active Drugs against Giardia lamblia
Twenty-nine of 34 (85%) Zn-finger-active compounds at 300 μM or less inhibited the growth of Giardia lamblia. The most active compound, disulfiram (Antabuse), was cidal at 1.23 ± 0.32 μM. In the adult mouse model, significant in vivo activity was demonstrated by increased cure rates and decreased pa...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC105627/ https://ncbi.nlm.nih.gov/pubmed/9624499 |
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