Delivery of the Non-Membrane-Permeative Antibiotic Gentamicin into Mammalian Cells by Using Shigella flexneri Membrane Vesicles

We developed a model to test whether non-membrane-permeative therapeutic agents such as gentamicin could be delivered into mammalian cells by means of bacterial membrane vesicles. Many gram-negative bacteria bleb off membrane vesicles (MVs) during normal growth, and the quantity of these vesicles ca...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Kadurugamuwa, Jagath L., Beveridge, Terry J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1476
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