A New Ketolide, HMR 3004, Active against Streptococci Inducibly Resistant to Erythromycin

HMR 3004 is a new hydrazono ketolide characterized by a 3-keto function instead of the cladinose moiety. The effect of this antimicrobial agent on inducible and constitutive macrolide-lincosamide-streptogramin B (MLS(B)) resistance was tested in a lacZ reporter system under control of several ermAM-...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Rosato, Adriana, Vicarini, Hubert, Bonnefoy, Alain, Chantot, Jean-François, Leclercq, Roland
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1392
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