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Assessment of Antifungal Activities of Fluconazole and Amphotericin B Administered Alone and in Combination against Candida albicans by Using a Dynamic In Vitro Mycotic Infection Model

We evaluated the pharmacodynamic activities of fluconazole and amphotericin B given alone and in combination against Candida albicans by using an in vitro model of bloodstream infection that simulates human serum pharmacokinetic parameters for these antifungals. Fluconazole was administered as a bol...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lewis, Russell E., Lund, Brian C., Klepser, Michael E., Ernst, Erika J., Pfaller, Michael A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105608/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1382
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