Recombinant Expression and Characterization of the Major β-Lactamase of Mycobacterium tuberculosis

New antibiotic regimens are needed for the treatment of multidrug-resistant tuberculosis. Mycobacterium tuberculosis has a thick peptidoglycan layer, and the penicillin-binding proteins involved in its biosynthesis are inhibited by clinically relevant concentrations of β-lactam antibiotics. β-Lactam...

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Huvudupphovsmän: Voladri, Rama Kishan R., Lakey, David L., Hennigan, Steven H., Menzies, Barbara E., Edwards, Kathryn M., Kernodle, Douglas S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC105607/
https://ncbi.nlm.nih.gov/pubmed/9624479
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