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Initial Concentration-Time Profile of Gentamicin Determines Efficacy against Enterobacter cloacae ATCC 13047

In vitro studies were designed to investigate the influence of peak drug concentration (C(max)), the area under the concentration-time curve (AUC), and, consequently, the trough concentration on the bactericidal effects of gentamicin against Enterobacter cloacae (MIC, 0.5 mg/liter) by simulating bol...

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Detalhes bibliográficos
Main Authors: Rayner, Craig R., Ioannides-Demos, Lisa L., Brien, Jo-Anne E., Liolios, Lisa L., Spicer, W. John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105606/
https://ncbi.nlm.nih.gov/pubmed/9624478
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