Initial Concentration-Time Profile of Gentamicin Determines Efficacy against Enterobacter cloacae ATCC 13047

In vitro studies were designed to investigate the influence of peak drug concentration (C(max)), the area under the concentration-time curve (AUC), and, consequently, the trough concentration on the bactericidal effects of gentamicin against Enterobacter cloacae (MIC, 0.5 mg/liter) by simulating bol...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Rayner, Craig R., Ioannides-Demos, Lisa L., Brien, Jo-Anne E., Liolios, Lisa L., Spicer, W. John
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Pharmacology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1370
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