Phenotypic Study of Resistance of β-Lactamase-Inhibitor-Resistant TEM Enzymes Which Differ by Naturally Occurring Variations and by Site-Directed Substitution at Asp(276)

At this time an amino acid substitution at position 276 in the TEM-1 enzyme is associated with an additional substitution at position 69 in natural β-lactamase-inhibitor-resistant (IRT) β-lactamases. The effect of the Asn(276)→Asp substitution on resistance was assessed with the Asn276Asp variant, g...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Caniça, M. Manuela, Caroff, Nathalie, Barthélémy, Michel, Labia, Roger, Krishnamoorthy, Rajagopal, Paul, Gérard, Dupret, Jean-Marie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1323
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!