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Fluconazole Pharmacokinetics in Burn Patients

The pharmacokinetics of fluconazole in nine adult patients with severe (30 to 95% total body surface area) burns were studied. There was no significant difference in half-life (t(1/2)), clearance (CL), or volume of distribution (V) over time in five patients on days 3 and 8 of the study (P > 0.05)....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Boucher, Bradley A., King, Stephen R., Wandschneider, Heidi L., Hickerson, William L., Hanes, Scott D., Herring, Vanessa L., Canada, Todd W., Hess, Mary M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105570/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.930
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