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Dual Inhibition of Human Rhinovirus 2A and 3C Proteases by Homophthalimides

The 2A and 3C proteases encoded by human rhinoviruses (HRVs) are attractive targets for antiviral drug development due to their important roles in viral replication. Homophthalimides were originally identified as inhibitors of rhinovirus 3C protease through our screening effort. Previous studies hav...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Wang, Q. May, Johnson, Robert B., Jungheim, Louis N., Cohen, Jeffrey D., Villarreal, Elcira C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.916
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