Double-Blind Evaluation of the Safety and Pharmacokinetics of Multiple Oral Once-Daily 750-Milligram and 1-Gram Doses of Levofloxacin in Healthy Volunteers

The safety and pharmacokinetics of once-daily oral levofloxacin in 16 healthy male volunteers were investigated in a randomized, double-blind, placebo-controlled study. Subjects were randomly assigned to the treatment (n = 10) or placebo group (n = 6). In study period 1, 750 mg of levofloxacin or a...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Chien, Shu-Chean, Wong, Frank A., Fowler, Cynthia L., Callery-D’Amico, Susan V., Williams, R. Rex, Nayak, Ramchandra, Chow, Andrew T.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.885
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