Unique Metabolism of a Novel Antiviral l-Nucleoside Analog, 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil: a Substrate for Both Thymidine Kinase and Deoxycytidine Kinase

2′-Fluoro-5-methyl-β-l-arabinofuranosyluracil (l-FMAU) is the first l-nucleoside analog with low cytotoxicity discovered to have potent antiviral activities against both hepatitis B virus and Epstein-Barr virus but not human immunodeficiency virus. This spectrum of activity is different from those o...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Liu, Shwu-Huey, Grove, Kristie L., Cheng, Yung-Chi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.833
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!