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Effect of Terbinafine on Theophylline Pharmacokinetics in Healthy Volunteers

Twelve healthy volunteers were enrolled in an open-label, randomized, crossover study. Subjects received single doses of theophylline (5 mg/kg) with and without multiple-dose terbinafine, and 11 blood samples were collected over 24 h. The study phases were separated by a 4-week washout period. Theop...

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Detalhes bibliográficos
Main Authors: Trépanier, Eric F., Nafziger, Anne N., Amsden, Guy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105520/
https://ncbi.nlm.nih.gov/pubmed/9517954
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