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In Vitro and In Vivo Antibacterial Activities of CS-834, a New Oral Carbapenem

CS-834 is a prodrug of the carbapenem R-95867, developed by Sankyo Co., Ltd., Tokyo, Japan. To investigate the possibility that CS-834 may be the first carbapenem usable in an oral dosage form, its in vitro antibacterial activity (as R-95867) and in vivo antibacterial activity were compared with tho...

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Main Authors: Yamaguchi, Keizo, Domon, Haruki, Miyazaki, Shuichi, Tateda, Kazuhiro, Ohno, Akira, Ishii, Kazuhiro, Matsumoto, Tetsuya, Furuya, Nobuhiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC105498/
https://ncbi.nlm.nih.gov/pubmed/9517932
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