QacA Multidrug Efflux Pump from Staphylococcus aureus: Comparative Analysis of Resistance to Diamidines, Biguanidines, and Guanylhydrazones

The staphylococcal multidrug efflux pump QacA mediates resistance to a broad spectrum of monovalent and divalent antimicrobial cations. Resistance toward various classes of these compounds identified features of the substrate that may be important for interaction with QacA. Analysis of combinations...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Mitchell, Bernadette A., Brown, Melissa H., Skurray, Ronald A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Resistance
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105442/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.475
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