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Death begets failure in the heart

Recently, low — but abnormal — rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implicatio...

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Autors principals: Foo, Roger S.-Y., Mani, Kartik, Kitsis, Richard N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1052022/
https://ncbi.nlm.nih.gov/pubmed/15765138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200524569
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