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Metachromatic leucodystrophy (MLD) in a patient with a constitutional ring chromosome 22

Metachromatic leucodystrophy (MLD) is an autosomal recessive lysosomal storage disease resulting from a severe deficiency of arylsulphatase A. The arylsulphatase A gene is located on chromosome 22 at q13.3. An MLD patient is described who carries a common splicing mutation (“I” allele) and a de novo...

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Autori principali: Coulter-Mackie, M B, Rip, J, Ludman, M D, Beis, J, Cole, D E C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051701/
https://ncbi.nlm.nih.gov/pubmed/8558556
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