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Genomic imprinting: a possible mechanism for the parental origin effect in Huntington's chorea.

Huntington's disease (HD) is an autosomal dominant condition with almost complete penetrance. The age of onset of the symptoms, however, is variable and depends on the parental origin of the gene. A high proportion of early onset cases inherit the HD gene from their father, whereas a considerab...

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Hlavní autor: Reik, W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051607/
https://ncbi.nlm.nih.gov/pubmed/2976840
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