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Septo-optic dysplasia and WS1 in the proband of a WS1 family segregating for a novel mutation in PAX3 exon 7.

A four generation family (UoM1) was ascertained with Waardenburg syndrome type 1 (WS1). The proband exhibited both WS1 and septo-optic dysplasia. A G to C transversion was identified in PAX3 exon 7 in four subjects affected with WS1 in this family including the proband. This glutamine to histidine m...

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Bibliographic Details
Main Authors: Carey, M L, Friedman, T B, Asher, J H, Innis, J W
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051252/
https://ncbi.nlm.nih.gov/pubmed/9541113
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