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Misleading linkage results in an NF2 presymptomatic test owing to mosaicism.

A two generation family with neurofibromatosis type 2 (NF2) is presented in which a family member requested presymptomatic molecular diagnosis. Since the consultand's mother had clinically well defined NF2, he was quoted to be at 50% risk of carrying an NF2 mutation. Mutation screening in the m...

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Detalhes bibliográficos
Main Authors: Bijlsma, E K, Wallace, A J, Evans, D G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051124/
https://ncbi.nlm.nih.gov/pubmed/9391890
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